Facilities
The School has outstanding facilities, with for example 9 high resolution NMR spectrometers and 1 solid state, 3 area detectors and several powder systems for X-ray crystallography, and it hosts a national EPR service. Its research has been recognised both by funding bodies, who are currently providing over £40M of research grants, and by numerous national and international prizes and awards.
Our research community includes over 70 postdoctoral researchers and 220 postgraduate students. We have research links with over 80 different companies and over 150 overseas universities and research institutes.
Chromatography
GC- Three autosampler based GC instruments with FID detection, on line data acquisition and processing, allied to GC-MS facility.
Contact - Carole Webb
HPLC - All new autosampler based analytical instrumentation with UV/3D spectral detection, also RI detection. Foward and reverse phase. Preparative scale HPLC with variable wavelength detection.
Contact - Rehana Sung
- Electrospray (ES) A good general technique,for polar organic or organometallic molecules, salts and acids. Maximum mass ~ 2800
- Atmospheric Pressure Chemical Ionisation (APCI) Better than ES for non-polar compounds
- Electron Impact / Chemical Ionisation (EI/CI) Use for organic samples that melt below ~250 deg and have a molecular mass less than ~500.
- Matrix Assisted Laser Desorption Ionisation (MALDI) Polymers, organometallics and high mass samples.
- Gas Chromatography and Liquid Chromatography Mass Spectrometry (GCMS and LCMS)
- High Resolution Accurate Mass Measurements Upper mass limit is ~ 1,000
Contact - Rehana Sung, Gareth Smith
- Carbon, Hydrogen, Nitrogen, Sulphur analysis (CHNS)
- Differential Scanning Calorimetry (DSC)
- Metals analysis by Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES).
- Halide analysis (Chlorine, Bromine, Iodine) by potentiometric autotitrator.
- Thermogravimetric Analyis (TGA)
Contact - Martin Jennings
• Proton
• Carbon
• DEPT (Distortionless Enhancement by Polarization Transfer)
• COSY (COrrelation SpectroscopY)
• HSQC (Heteronuclear Single-Quantum Correlation)
• HMBC (Heteronuclear Multiple Bond Correlation)
• 31P
• 19F
• NOESY (Nuclear Overhauser Effect SpectroscopY)
• 7Li
• 11B
• other nuclei
• ROESY (Rotating frame nuclear Overhauser Effect SpectroscopY)
• TOCSY (Total correlation spectroscopy)
• 1D NOESY(nOe) (Nuclear Overhauser effect)
• water suppression inc. 2D expts
• Variable Temperature, standard range 120 deg C to -40 deg C. depending on solvent.
• Time-course studies
Contact - Roger Speak
MIB contact for NMR - Barbara Gore
Loacation - Basement
NMR from Solids
Contact - Barbara Gore
Location - Basement
Optical Spectroscopy
UV-visible spectroscopy with diode array detection, range 190- 900 nm. Peltier-controlled cell compartment for temperature studies.
Infra- red spectroscopy: Near, mid and far infrared transmission studies, film, liquid or reflection accessories.
Dedicated diamond crystal ATR instrument for solid and liquid samples in mid IR
Contact - Roger Speak
Single Crystal full structure determinations
- Variable Temperature (VT) 100-400 K
- Air Sensitive
Powder X-Ray Diffraction (XRD)
- Variable Temperature (VT) 300 – 1100 K
- Reduced pressure – 1 mbar
- High Pressure – 10 bar
- Continuous gas flow
Small Angle X-Ray Scattering (SAXS)
- Variable Temperature (VT) 250 – 600 K
- Gels
- Powders
- Liquids
- Continuous liquid flow
Grazing Incidence Small Angle X-Ray Scattering (GISAXS)
Contact - Chris Muryn, Jim Raftery
Location - 5.62