Prof Jason Micklefield (PhD) - personal details


 

Contact details

Prof Jason Micklefield

Role: Professor of Chemical Biology

Email:

Tel: 0161 306-4509

Location: Manchester Institute of Biotechnology-2.015
School of Chemistry
The University of Manchester
Manchester
M13 9PL

Websites

 

Biography

Jason Micklefield is Professor of Chemical Biology within the School of Chemistry and the Manchester Institute of Biotechnology. He graduated from the University of Cambridge in 1993 with a PhD in Chemistry, working with Prof Sir Alan R. Battersby FRS to complete the first total synthesis of haem d1. He then moved to the University of Washington, USA, as a NATO postdoctoral fellow investigating various biosynthetic pathways and enzyme mechanisms with Prof Heinz G. Floss. In 1995 he began his independent research career as a Lecturer in Organic Chemistry at Birkbeck College, University of London before moving to Manchester in 1998.

Awards and Appointments

Fellowships & awards: RSC Natural Product Reports (NPR) lecture award (2008); Elected fellow of the Royal Society of Chemistry, FRSC (2006); Gilead Sciences Inc. (USA) Scholarship (2000); NATO Fellowship (1993-1995); BP Award (Final Year Undergraduate Chemistry Prize); Tioxide Award (1st Year Undergraduate Chemistry Prize).
 
Appointments: Editorial advisory board of Chem. Commun. (2003-2006); Editorial board of Current Organic Synthesis (2003-2009) & Marine Drugs (2008-); Former consultant for RecombinoGen Ltd, Gerson Lehrman Group, INEOS Fluor; Committee member RSC Bio-organic group (2006-11) and Nucleic acid group (2004-); EPSRC Peer Review College (2005-); BBSRC Research Committee (core member) (2009-11); Deutsche Forschungsgemeinschaft (DFG) International Review Panel (Excellence Initiative); Director of Research School of Chemistry, University of Manchester (2008-2011); Director Manchester Chemical Biology Network

Current Funding

Current publicly funded research awards (excluding studentships & industrial awards):
2012-13 BBSRC (BB/J019089/1) Feasibility and Benchmarking of RiboTite gene expression control technology (PI), £146,160
2012-15 BBSRC (BB/I012648/1) Orthogonal riboswitches as tools for controlling gene expression in bacteria (PI), £652,206
2011-13 EPSRC (EP/I037253/1) The Manchester Chemical Biology Network (PI), £144,333
2011-14 BBSRC (BB/I020764/1) Directed Evolution of Enantiocomplementary Malonate Decarboxylases (PI), £318,552
2011-14 BBSRC (BB/I008055/1) Bioorthogonal site-selective protein immobilisation and labelling (PI), £472,039
2010-12 EPSRC KTA Manchester centre for chemical intervention in biology and medicine (Co-I), £179,677
2008-13 BBSRC Lola (BB/F000537/1) Dynamically-coupled enzyme catalysis: towards a step change in our understanding of enzyme catalysed reactions (Co-I), £2,402,423

Selected Invited Lectures

Selected international conference & overseas lectures: Zing Biocatalysis Conference, Cancun, Mexico (2012); Synthetic Biology Symposium, National Academy of Sciences, Washington DC, USA (2012); Keynote, 9th Foundations of Nanoscience Meeting (FNANO12), Utah, USA (2012); Zing Natural Products, Lanzerote, Spain (2012); RSC Challenges in Chemical Biology (ISACS5), UK (2011); Plenary, XV Symposium on the Chemistry of Nucleic Acids (SCNAC), eský Krumlov, Czech Republic (2011); BASF Ludwigshafen, Germany (2010); Gordon research conference, Biocatalysis, RI, USA (2010); Frontiers in Chemical Biology, University of Leeds (2009); Firbush Conference on Bioorganic Chemistry, Scotland (2009); RSC Functional Molecules from Natural Sources, Magdalen College, Oxford (2009); Organisch-chemisches Institut, Universität Zürich, Switzerland (2009); Japan-UK Bilateral Meeting on Genomics and Biosynthesis of Antibiotic Production, Tokyo, Japan (2008); GSK, Stevenage and live broadcast to GSK R&D worldwide (2008); RSC Chemistry in the New World of Bioengineering and Synthetic Biology, Oxford (2008); 4th International Congress on Biocatalysis (Biocat2008), Hamburg, Germany, (2008); Plenary Award Lecture, IUPAC Conference on Biodiversity and Natural Products (ICOB-6 and ISCNP-26), Prince Edward Island, Canada (2008); XIV Symposium on the Chemistry of Nucleic Acids (SCNAC), eský Krumlov, Czech Republic (2008); Institut de Recherches Microbiologiques J-M Wiame, Université Libre de Bruxelles (2007); Firbush Conference on Bioorganic Chemistry (2007); 10th International Symposium on Natural Product Chemistry Karachi, Pakistan (2006); 40th European Symposium on Bio-Organic Chemistry (ESBOC), Gregynog, Wales (2006); RSC Directing Biosynthesis, Cambridge (2006); University of  Marburg, Germany (2005); The 1st European Conference on Chemistry for Life Sciences, Rimini, Italy (2005); RSC Nucleic Acids Chemistry Towards Biology: 50 Years On, MRC, Cambridge (2005); Beilsein-Institut, The Chemical Theatre of Biological Systems, Bozen, Italy (2004); 7th International Symposium on Biomolecular Chemistry - ISBOC-7, Sheffield (2004); Nucleic Acid Chemical Biology, Odense, Denmark (2003); The Spinks Symposium, London (2003); Departamento de Quimica Organica, Univ de Zaragoza, Spain (2002).

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