Prof Jonathan Waltho - publications


List of publications


  • Czarnota, S., Baxter, N., Cliff, M. J., Waltho, J., Scrutton, N., & Hay, S. (2017). 1H, 15N, 13C backbone resonance assignments of human soluble catechol Omethyltransferase in complex with S-adenosyl-L-methionine and 3,5-dinitrocatechol. Biomolecular NMR Assignments. DOI: 10.1007/s12104-016-9720-9. Publication link: 081c9a3b-352c-41b6-ada1-c72f70469efc


  • Jin, Y., Molt, R. W., Waltho, J. P., Richards, N. G. J., & Blackburn, G. M. (2016). 19F NMR and DFT Analysis Reveal Structural and Electronic Transition State Features for RhoA-Catalyzed GTP Hydrolysis. Angewandte Chemie (International Edition). DOI: 10.1002/anie.201509477. Publication link: 3be98d53-8e90-4405-9876-0ee99d0d1eb8
  • Jin, Y., Richards, N. G. J., Waltho, J., & Blackburn, G. M. (2016). Metal Fluorides as Analogs for Studies on Phosphoryl Transfer Enzymes. Angewandte Chemie. . Publication link: 351c0776-9d41-4425-a5fb-dad9ba68dc32



  • Krishnan, R., Tsubery, H., Proschitsky, M. Y., Asp, E., Lulu, M., Gilead, S., ... Fisher, R. A. (2014). A bacteriophage capsid protein provides a general amyloid interaction motif (GAIM) that binds and remodels misfolded protein assemblies.Journal of molecular biology, 426(13). DOI: 10.1016/j.jmb.2014.04.015. Publication link: 06b3ec16-2f6d-442c-b697-4dcbe396c6f8 | PubMed:24768993
  • Trevitt, C. R., Hosszu, L. L. P., Batchelor, M., Panico, S., Terry, C., Nicoll, A. J., ... Clarke, A. R. (2014). N-terminal domain of prion protein directs its oligomeric association.The Journal of biological chemistry, 289(37). DOI: 10.1074/jbc.M114.566588. Publication link: 1a4defa7-4f8e-41c6-bf41-1320df065f38 | PubMed:25074940
  • Jin, Y., Bhattasali, D., Pellegrini, E., Forget, S. M., Baxter, N. J., Cliff, M. J., ... Waltho, J. P. (2014). α-Fluorophosphonates reveal how a phosphomutase conserves transition state conformation over hexose recognition in its two-step reaction.Proceedings of the National Academy of Sciences of the United States of America, 111(34). DOI: 10.1073/pnas.1402850111. Publication link: e4faa1db-a739-49be-92f2-4455003fd7c7 | PubMed:25104750


  • Paudel, L., Adams, R. W., Kiraly, P., Aguilar Malavia, J., Foroozandeh, M., Cliff, M., ... Morris, G. A. (2013). Simultaneously enhancing spectral resolution and sensitivity in heteronuclear correlation NMR spectroscopy.Angewandte Chemie (International ed. in English), 52(44), 11616-11619. DOI: 10.1002/anie.201305709. Publication link: e6c6b2d3-bb1e-4058-aaa3-e3e0b5dbe23e | PubMed:24014213
  • Pudney, C. R., Guerriero, A., Baxter, N. J., Johannissen, L. O., Waltho, J. P., Hay, S., & Scrutton, N. S. (2013). Fast protein motions are coupled to enzyme H-transfer reactions.Journal of the American Chemical Society, 135(7), 2512-2517. DOI: 10.1021/ja311277k. Publication link: 66e5a165-10c4-4818-b9db-65ad1ead3514 | PubMed:23373704


  • Jin, Y., Cliff, M. J., Baxter, N. J., Dannatt, H. R. W., Hounslow, A. M., Bowler, M. W., ... Waltho, J. P. (2012). Charge-balanced metal fluoride complexes for protein kinase A with adenosine diphosphate and substrate peptide SP20.Angewandte Chemie (International ed. in English), 51(49), 12242-12245. DOI: 10.1002/anie.201204266. Publication link: 92fcd92e-9b1e-4e9f-ae4f-3e21b978b943 | PubMed:23125010
  • Paramore, R., Morgan, G. J., Davis, P. J., Sharma, C. A., Hounslow, A., Taler-Verčič, A., ... Zerovnik, E. (2012). Mapping local structural perturbations in the native state of stefin B (cystatin B) under amyloid forming conditions. Frontiers in Molecular Neuroscience, 5(2012), 1-30. DOI: 10.3389/fnmol.2012.00094. Publication link: 1bc20f4c-3ba2-4e1c-a3d8-78abec85bc05 | PubMed:23091450
  • Waltho, J., Kubota, T., Hamazoe, Y., Hashiguchi, S., Ishibashi, D., Akasaka, K., ... Sugimura, K. (2012). Direct evidence of generation and accumulation of β-sheet-rich prion protein in scrapie-infected neuroblastoma cells with human IgG1 antibody specific for β-form prion protein.The Journal of biological chemistry, 287(17). DOI: 10.1074/jbc.M111.318352. Publication link: b461d9ba-73cd-4209-9df9-10db37fc4011 | PubMed:22356913
  • Griffin, J. L., Bowler, M. W., Baxter, N. J., Leigh, K. N., Dannatt, H. R. W., Hounslow, A. M., ... Waltho, J. P. (2012). Near attack conformers dominate β-phosphoglucomutase complexes where geometry and charge distribution reflect those of substrate. Proceedings of the National Academy of Sciences of the United States of America, 109(18), 6910-6915. DOI: 10.1073/pnas.1116855109. Publication link: fb5551d5-8802-45d6-98ed-311f35cec5ed | PubMed:22505741
  • Blackburn, G. M., Bowler, M. W., Jin, Y., & Waltho, J. P. (2012). Reflections on biocatalysis involving phosphorus.Biochemistry. Biokhimii︠a︡, 77(10), 1083-1096. DOI: 10.1134/S000629791210001X. Publication link: fea0076b-e24d-4b98-af06-b46cf64e2727 | PubMed:23157289


  • Milanesi, L., Hunter, C. A., Tzokova, N., Waltho, J. P., & Tomas, S. (2011). Versatile low-molecular-weight hydrogelators: achieving multiresponsiveness through a modular design.Chemistry (Weinheim an der Bergstrasse, Germany), 17(35), 9753-9761. DOI: 10.1002/chem.201100640. Publication link: dadd0a04-9169-4560-b684-edd3516c573b | PubMed:21793058
  • Xiaoxia, L., Marston, J. P., Baxter, N. J., Hounslow, A. M., Yufen, Z., Blackburn, G. M., ... Waltho, J. P. (2011). Prioritization of charge over geometry in transition state analogues of a dual specificity protein kinase.Journal of the American Chemical Society, 133(11), 3989-3994. DOI: 10.1021/ja1090035. Publication link: c34a9942-a91d-411b-bb96-d2fc0db809ab | PubMed:21348513
  • Jelinska, C., Davis, P. J., Kenig, M., Zerovnik, E., Kokalj, S. J., Gunčar, G., ... Žerovnik, E. (2011). Modulation of contact order effects in the two-state folding of stefins A and B.Biophysical Journal, 100(9), 2268-2274. DOI: 10.1016/j.bpj.2011.03.024. Publication link: f8046928-971b-4e96-8417-3974e005c438 | PubMed:21539796


  • Marston, J. P., Cliff, M. J., Reed, M. A. C., Blackburn, G. M., Hounslow, A. M., Craven, C. J., & Waltho, J. P. (2010). Structural tightening and interdomain communication in the catalytic cycle of phosphoglycerate kinase.Journal of molecular biology, 396(2), 345-360. DOI: 10.1016/j.jmb.2009.11.052. Publication link: 8b44a8ba-12c5-4dd6-be64-f94ef2a17006 | PubMed:19944703
  • Nicoll, A. J., Trevitt, C. R., Tattum, M. H., Risse, E., Quarterman, E., Ibarra, A. A., ... Collinge, J. (2010). Pharmacological chaperone for the structured domain of human prion protein.Proceedings of the National Academy of Sciences of the United States of America, 107(41), 17610-17615. DOI: 10.1073/pnas.1009062107. Publication link: 7974e874-3189-418e-9834-d27d0ec8b237 | PubMed:20876144
  • Baxter, N. J., Bowler, M. W., Alizadeh, T., Cliff, M. J., Hounslow, A. M., Wu, B., ... Waltho, J. P. (2010). Atomic details of near-transition state conformers for enzyme phosphoryl transfer revealed by MgF-3 rather than by phosphoranes.Proceedings of the National Academy of Sciences of the United States of America, 107(10), 4555-4560. DOI: 10.1073/pnas.0910333106. Publication link: 4181eea4-426d-45f7-b248-b3f6fa085249 | PubMed:20164409
  • Cliff, M. J., Bowler, M. W., Varga, A., Marston, J. P., Szabó, J., Hounslow, A. M., ... Waltho, J. P. (2010). Transition state analogue structures of human phosphoglycerate kinase establish the importance of charge balance in catalysis. Journal of the American Chemical Society, 132(18), 6507-6516. DOI: 10.1021/ja100974t. Publication link: 4f50840f-dda1-4941-adac-40e53aca94a6 | PubMed:20397725
  • Hosszu, L. L. P., Tattum, M. H., Jones, S., Trevitt, C. R., Wells, M. A., Waltho, J. P., ... Clarke, A. R. (2010). The H187R mutation of the human prion protein induces conversion of recombinant prion protein to the PrP(Sc)-like form.Biochemistry, 49(40), 8729-8738. DOI: 10.1021/bi100572j. Publication link: aa76453c-e7cb-47fb-abf4-56d5f5a47c9e | PubMed:20718410


  • Baxter, N. J., Hounslow, A. M., Bowler, M. W., Williams, N. H., Blackburn, G. M., & Waltho, J. P. (2009). MgF(3)(-) and alpha-galactose 1-phosphate in the active site of beta-phosphoglucomutase form a transition state analogue of phosphoryl transfer.Journal of the American Chemical Society, 131(45), 16334-16335. DOI: 10.1021/ja905972m. Publication link: f7c96e40-5219-4c5a-9f2b-5ff896bbd98a | PubMed:19852484
  • Skerget, K., Vilfan, A., Pompe-Novak, M., Turk, V., Waltho, J. P., Turk, D., ... Žerovnik, E. (2009). The mechanism of amyloid-fibril formation by stefin B: temperature and protein concentration dependence of the rates.Proteins, 74(2), 425-436. DOI: 10.1002/prot.22156. Publication link: c8e75cfa-7034-48ea-bd5e-a915f403e439 | PubMed:18636508
  • Menon, B. R. K., Waltho, J. P., Scrutton, N. S., & Heyes, D. J. (2009). Cryogenic and laser photoexcitation studies identify multiple roles for active site residues in the light-driven enzyme protochlorophyllide oxidoreductase.The Journal of biological chemistry, 284(27), 18160-18166. DOI: 10.1074/jbc.M109.020719. Publication link: 12b65824-889d-4691-901e-a7e03b9aeebb | PubMed:19439417
  • Hart, T., Hosszu, L. L. P., Trevitt, C. R., Jackson, G. S., Waltho, J. P., Collinge, J., & Clarke, A. R. (2009). Folding kinetics of the human prion protein probed by temperature jump.Proceedings of the National Academy of Sciences of the United States of America, 106(14), 5651-5656. DOI: 10.1073/pnas.0811457106. Publication link: 4bc4f647-39e4-458a-a4fa-a6e56dd042fa | PubMed:19321423
  • Cliff, M. J., Craven, C. J., Marston, J. P., Hounslow, A. M., Clarke, A. R., & Waltho, J. P. (2009). The Denatured State of N-PGK Is Compact and Predominantly Disordered. Journal of Molecular Biology, 385(1), 266-277. DOI: 10.1016/j.jmb.2008.10.004. Publication link: 4a97fc09-fe6b-4deb-9571-6b57f3b398c0 | PubMed:18948115
  • Hosszu, L. L. P., Trevitt, C. R., Jones, S., Batchelor, M., Scott, D. J., Jackson, G. S., ... Clarke, A. R. (2009). Conformational properties of β-PrP. Journal of Biological Chemistry, 284(33), 21981-21990. DOI: 10.1074/jbc.M809173200. Publication link: 40257577-4ff7-44ba-91de-5ddbb59f28c9 | PubMed:19369250
  • Golicnik, M., Olguin, L. F., Feng, G., Baxter, N. J., Waltho, J. P., Williams, N. H., & Hollfelder, F. (2009). Kinetic analysis of beta-phosphoglucomutase and its inhibition by magnesium fluoride.Journal of the American Chemical Society, 131(4), 1575-1588. DOI: 10.1021/ja806421f. Publication link: 7b90e2ae-1cbb-4e28-ab6e-a0a4871444a4 | PubMed:19132841


  • Milanesi, L., Jelinska, C., Hunter, C. A., Hounslow, A. M., Staniforth, R. A., & Waltho, J. P. (2008). A method for the reversible trapping of proteins in non-native conformations. Biochemistry, 47(51), 13620-13634. DOI: 10.1021/bi801362f. Publication link: 049e2ccf-73fd-4012-b0c9-a063233d175b | PubMed:19035655
  • Baxter, N. J., Blackburn, G. M., Marston, J. P., Hounslow, A. M., Cliff, M. J., Bermel, W., ... Waltho, J. P. (2008). Anionic charge is prioritized over geometry in aluminum and magnesium fluoride transition state analogs of phosphoryl transfer enzymes.Journal of the American Chemical Society, 130(12), 3952-3958. DOI: 10.1021/ja078000n. Publication link: 1f7e3e00-73eb-4667-8376-512118c91a5d | PubMed:18318536
  • Milanesi, L., Tomas, S., Hunter, C. A., Weinstein, J. A., Edge, R., Navaratnam, S., ... Best, J. (2008). A pulse--radiolysis approach to fast reductive cleavage of a disulfide bond to uncage enzyme activity.Free Radical Biology & Medicine, 45(9), 1271-1278. DOI: 10.1016/j.freeradbiomed.2008.07.024. Publication link: 9c1af524-69a8-408a-a5cd-7877d005330c | PubMed:18760345
  • Morgan, G. J., Giannini, S., Hounslow, A. M., Craven, C. J., Zerovnik, E., Turk, V., ... Staniforth, R. A. (2008). Exclusion of the native alpha-helix from the amyloid fibrils of a mixed alpha/beta protein.Journal of molecular biology, 375(2), 487-498. DOI: 10.1016/j.jmb.2007.10.033. Publication link: 720015fd-0b5a-4d29-ac7b-006dfad4ff81 | PubMed:18021806



  • Reed, M. A. C., Jelinska, C., Syson, K., Cliff, M. J., Splevins, A., Alizadeh, T., ... Waltho, J. P. (2006). The denatured state under native conditions: a non-native-like collapsed state of N-PGK.Journal of molecular biology, 357(2), 365-372. DOI: 10.1016/j.jmb.2005.12.080. Publication link: 89858384-e068-4d8b-bf81-a3306c3a7020 | PubMed:16430920
  • Berrisford, J. M., Hounslow, A. M., Akerboom, J., Hagen, W. R., Brouns, S. J. J., van der Oost, J., ... Baker, P. J. (2006). Evidence supporting a cis-enediol-based mechanism for Pyrococcus furiosus phosphoglucose isomerase.Journal of molecular biology, 358(5), 1353-1366. DOI: 10.1016/j.jmb.2006.03.015. Publication link: 68a61acd-f3a5-4e54-97a1-580b6157bb55 | PubMed:16580686
  • Milanesi, L., Hunter, C. A., Sedelnikova, S. E., & Waltho, J. P. (2006). Amplification of bifunctional ligands for calmodulin from a dynamic combinatorial library.Chemistry (Weinheim an der Bergstrasse, Germany), 12(4), 1081-1087. DOI: 10.1002/chem.200500357. Publication link: 0305d508-bd37-4d45-a2f2-e89d68a596c7 | PubMed:16240315
  • Wells, M. A., Jelinska, C., Hosszu, L. L. P., Craven, C. J., Clarke, A. R., Collinge, J., ... Jackson, G. S. (2006). Multiple forms of copper (II) co-ordination occur throughout the disordered N-terminal region of the prion protein at pH 7.4.The Biochemical journal, 400(3), 501-510. DOI: 10.1042/BJ20060721. Publication link: b386ac6b-f3ba-4258-94fa-cf9c40a9734b | PubMed:16925523
  • Baxter, N. J., Olguin, L. F., Golicnik, M., Feng, G., Hounslow, A. M., Bermel, W., ... Williams, N. H. (2006). A Trojan horse transition state analogue generated by MgF3- formation in an enzyme active site.Proceedings of the National Academy of Sciences of the United States of America, 103(40), 14732-14737. DOI: 10.1073/pnas.0604448103. Publication link: bcf4855d-6c78-4d1d-82e5-37fb7918cd7a | PubMed:16990434
  • Cliff, M. J., Alizadeh, T., Jelinska, C., Craven, C. J., Staniforth, R. A., & Waltho, J. P. (2006). A thiol labelling competition experiment as a probe for sidechain packing in the kinetic folding intermediate of N-PGK.Journal of molecular biology, 364(4), 810-823. DOI: 10.1016/j.jmb.2006.09.014. Publication link: a6884eaf-7997-4d97-9cef-4b5c733db1ee | PubMed:17030040
  • Baxter, N. J., Roetzer, A., Liebig, H-D., Sedelnikova, S. E., Hounslow, A. M., Skern, T., & Waltho, J. P. (2006). Structure and dynamics of coxsackievirus B4 2A proteinase, an enyzme involved in the etiology of heart disease.Journal of Virology, 80(3), 1451-1462. DOI: 10.1128/JVI.80.3.1451-1462.2006. Publication link: d7369ad2-df45-40b9-8cbe-d82a5476fc8b | PubMed:16415022
  • Wells, M. A., Jackson, G. S., Jones, S., Hosszu, L. L. P., Craven, C. J., Clarke, A. R., ... Waltho, J. P. (2006). A reassessment of copper(II) binding in the full-length prion protein.The Biochemical journal, 399(3), 435-444. DOI: 10.1042/BJ20060458. Publication link: f9184b7e-2f6a-4d52-a110-0a454d322843 | PubMed:16824036
  • Kenig, M., Jenko-Kokalj, S., Tušek-Žnidarič, M., Pompe-Novak, M., Gunčar, G., Turk, D., ... Zerovnik, E. (2006). Folding and amyloid-fibril formation for a series of human stefins' chimeras: Any correlation?Proteins: Structure, Function and Bioinformatics, 62(4), 918-927. DOI: 10.1002/prot.20812. Publication link: ef966852-3963-44c9-9b3c-70e67ada9111 | PubMed:16342276


  • Zhong, Q., Watson, M. J., Lazar, C. S., Hounslow, A. M., Waltho, J. P., & Gill, G. N. (2005). Determinants of the endosomal localization of sorting nexin 1. Molecular Biology of the Cell, 16(4), 2049-2057. DOI: 10.1091/mbc.E04-06-0504. Publication link: 48330c81-bfbb-428c-ad7b-c69244465a78 | PubMed:15673616
  • Jelinska, C., Conroy, M. J., Craven, C. J., Hounslow, A. M., Bullough, P. A., Waltho, J. P., ... White, M. F. (2005). Obligate heterodimerization of the archaeal Alba2 protein with Alba1 provides a mechanism for control of DNA packaging.Structure (London, England : 1993), 13(7), 963-971. DOI: 10.1016/j.str.2005.04.016. Publication link: 2c2c265c-5641-4787-ba8a-93de2dd58f85 | PubMed:16004869
  • Syson, K., Thirlway, J., Hounslow, A. M., Soultanas, P., & Waltho, J. P. (2005). Solution structure of the helicase-interaction domain of the primase DnaG: A model for helicase activation. Structure, 13(4), 609-616. DOI: 10.1016/j.str.2005.01.022. Publication link: 7d95ce27-91ce-4dcb-91cb-4f6bacdf8a1a | PubMed:15837199
  • Hosszu, L. L. P., Wells, M. A., Jackson, G. S., Jones, S., Batchelor, M., Clarke, A. R., ... Collinge, J. (2005). Definable equilibrium states in the folding of human prion protein.Biochemistry, 44(50), 16649-16657. DOI: 10.1021/bi051277k. Publication link: a6b5dee9-f39c-48f5-b0a8-878dcde1ee31 | PubMed:16342955
  • Trevitt, C. R., Craven, C. J., Milanesi, L., Syson, K., Mattinen, M. L., Perkins, J., ... Waltho, J. P. (2005). Enhanced ligand affinity for receptors in which components of the binding site are independently mobile. Chemistry and Biology, 12(1), 89-97. DOI: 10.1016/j.chembiol.2004.11.007. Publication link: d669e87c-f245-4388-80a1-cad63748ef01 | PubMed:15664518


  • Cliff, M. J., Higgins, L. D., Sessions, R. B., Waltho, J. P., & Clarke, A. R. (2004). Beyond the EX1 Limit: Probing the Structure of High-energy States in Protein Unfolding. Journal of Molecular Biology, 336(2), 497-508. DOI: 10.1016/j.jmb.2003.12.042. Publication link: d8a8c46d-5b77-478c-8602-2438b6160994 | PubMed:14757061
  • Japelj, B., Waltho, J. P., & Jerala, R. (2004). Comparison of Backbone Dynamics of Monomeric and Domain-Swapped Stefin A. Proteins: Structure, Function and Bioinformatics, 54(3), 500-512. DOI: 10.1002/prot.10624. Publication link: fa904cc3-89b8-4776-971e-26fc5014b90c | PubMed:14747998
  • Milanesi, L., Reid, G. D., Beddard, G. S., Hunter, C. A., & Waltho, J. P. (2004). Synthesis and Photochemistry of a New Class of Photocleavable Protein Cross-linking Reagents. Chemistry - A European Journal, 10(7), 1705-1710. DOI: 10.1002/chem.200305405. Publication link: 9cde0050-8a40-4365-85b5-d65709c85f9d | PubMed:15054757
  • Hosszu, L. L. P., Jackson, G. S., Trevitt, C. R., Jones, S., Batchelor, M., Bhelt, D., ... Collinge, J. (2004). The residue 129 polymorphism in human prion protein does not confer susceptibility to Creutzfeldt-Jakob disease by altering the structure or global stability of PrPc. Journal of Biological Chemistry, 279(27), 28515-28521. DOI: 10.1074/jbc.M313762200. Publication link: 290ab0ef-c8aa-4dfc-861d-4aeb1abfabd9 | PubMed:15123682
  • Sanders, A., Jeremy Craven, C., Higgins, L. D., Giannini, S., Conroy, M. J., Hounslow, A. M., ... Staniforth, R. A. (2004). Cystatin forms a Tetramer through Structural Rearrangement of Domain-swapped Dimers prior to Amyloidogenesis. Journal of Molecular Biology, 336(1), 165-178. DOI: 10.1016/j.jmb.2003.12.011. Publication link: 0f6ba237-eeb6-4796-8049-227e021714ea | PubMed:14741212


  • Reed, M. A. C., Hounslow, A. M., Sze, K. H., Barsukov, I. G., Hosszu, L. L. P., Clarke, A. R., ... Waltho, J. P. (2003). Effects of Domain Dissection on the Folding and Stability of the 43 kDa Protein PGK Probed by NMR. Journal of Molecular Biology, 330(5), 1189-1201. DOI: 10.1016/S0022-2836(03)00625-9. Publication link: 7756a4ba-f6c3-4727-9f07-4166e6433eeb | PubMed:12860138
  • Bailey, S., Sedelnikova, S. E., Mesa, P., Ayora, S., Waltho, J. P., Ashcroft, A. E., ... Rafferty, J. B. (2003). Structural analysis of Bacillus subtilis SPP1 phage helicase loader protein G39P. Journal of Biological Chemistry, 278(17), 15304-15312. DOI: 10.1074/jbc.M209300200. Publication link: c7d0edd0-bff3-4361-bd07-62751f466a0e | PubMed:12588876



  • Staniforth, R. A., Giannini, S., Higgins, L. D., Conroy, M. J., Hounslow, A. M., Jerala, R., ... Waltho, J. P. (2001). Three-dimensional domain swapping in the folded and molten-globule states of cystatins, an amyloid-forming structural superfamily. EMBO Journal, 20(17), 4774-4781. DOI: 10.1093/emboj/20.17.4774. Publication link: 8935d199-6123-4b11-8561-d61c85648f62 | PubMed:11532941
  • Jackson, G. S., Murray, I., Hosszu, L. L. P., Gibbs, N., Waltho, J. P., Clarke, A. R., & Collinge, J. (2001). Location and properties of metal-binding sites on the human prion protein. Proceedings of the National Academy of Sciences of the United States of America, 98(15), 8531-8535. DOI: 10.1073/pnas.151038498. Publication link: 5be27e1e-7555-4ca0-87c1-740e2a6481fd | PubMed:11438695
  • Thaw, P., Baxter, N. J., Hounslow, A. M., Price, C., Waltho, J. P., & Craven, C. J. (2001). Structure of TCTP reveals unexpected relationship with guanine nucleotide-free chaperones. Nature Structural Biology, 8(8), 701-704. DOI: 10.1038/90415. Publication link: a83d37e8-2d53-4fd3-977d-91d9f22a5267 | PubMed:11473261


  • Craven, C. J., Baxter, N. J., Murray, E. H., Hill, N. J., Martin, J. R., Ylinenjärvi, K., ... Murray, I. A. (2000). Wild-type and met-65 → Leu variants of human cystatin A are functionally and structurally identical. Biochemistry, 39(51), 15783-15790. DOI: 10.1021/bi0017069. Publication link: ebfc1958-8b0e-4d5d-baae-2b9105bfc142 | PubMed:11123903


  • Hurd, P. J., Whitmarsh, A. J., Baldwin, G. S., Kelly, S. M., Waltho, J. P., Price, N. C., ... Hornby, D. P. (1999). Mechanism-based inhibition of C5-cytosine DNA methyltransferases by 2-H pyrimidinone. Journal of Molecular Biology, 286(2), 389-401. DOI: 10.1006/jmbi.1998.2491. Publication link: 0abd6bda-59df-4727-9937-dded5427a50e | PubMed:9973559


  • Shore, P., Whitmarsh, A. J., Bhaskaran, R., Davis, R. J., Waltho, J. P., & Sharrocks, A. D. (1996). Determinants of DNA-binding specificity of ETS-domain transcription factors. Molecular and Cellular Biology, 16(7), 3338-3349. . Publication link: 69a7bd2e-8405-434d-a656-4637325f793a | PubMed:8668149



  • Hornby, D. P., Whitmarsh, A., Pinarbasi, H., Kelly, S. M., Price, N. C., Shore, P., ... Waltho, J. (1994). The DNA recognition subunit of a DNA methyltransferase is predominantly a molten globule in the absence of DNA. FEBS Letters, 355(1), 57-60. DOI: 10.1016/0014-5793(94)01171-0. Publication link: fbe5d648-1297-4985-b0b8-46380a38a2ea | PubMed:7957963

Personal details | Publications | Teaching

▲ Up to the top