Prof John Sutherland
Professor
Room Number: 2.27
Location: Chemistry Building
Tel: +44 (0)161-275-4614
Email: john.d.sutherland@manchester.ac.uk
Research Grouping: Organic Chemistry
Keywords
- Biological chemistry
- Evolution
- Prebiotic chemistry
- Nucleic acids
- Novel catalyst screening methods
- Metabolic pathway engineering
Research Interests
Our research in biological chemistry is concerned with two aspects of evolution. We have an ongoing research programme in prebiotic chemistry
focussing on the evolution of nucleic acids and genetically-coded proteins. This work involves synthetic and analytical chemistry. The second research area is concerned with exploiting evolutionary methods for the discovery of new chemical and biological catalysts. We are developing new methods for the creation and screening of chemical and biological diversity. Our targets are hybrid, green fermentation/chemical routes to important pharmaceutical intermediates and products. This work is highly interdisciplinary and involves, molecular biology, synthesis, automated
screen development and microbiology. Students and postdocs from both research areas acquire diverse skills in synthetic and biological chemistry. Recent destinations for past members of the group include Cambridge University (4), Glaxo-Wellcome (2), Cambridge Antibody Technology, Maxygen, Phylos, Harvard Medical School, Sense Therapeutic, Loughborough University, St. Judes Childrens Hospital, Biotica, Oxford University, BP-Amoco and The Scripps Research Institute.
focussing on the evolution of nucleic acids and genetically-coded proteins. This work involves synthetic and analytical chemistry. The second research area is concerned with exploiting evolutionary methods for the discovery of new chemical and biological catalysts. We are developing new methods for the creation and screening of chemical and biological diversity. Our targets are hybrid, green fermentation/chemical routes to important pharmaceutical intermediates and products. This work is highly interdisciplinary and involves, molecular biology, synthesis, automated
screen development and microbiology. Students and postdocs from both research areas acquire diverse skills in synthetic and biological chemistry. Recent destinations for past members of the group include Cambridge University (4), Glaxo-Wellcome (2), Cambridge Antibody Technology, Maxygen, Phylos, Harvard Medical School, Sense Therapeutic, Loughborough University, St. Judes Childrens Hospital, Biotica, Oxford University, BP-Amoco and The Scripps Research Institute.
Career
BA Hons Chemistry, Oxford 1984. Kennedy Scholar, Harvard 1984. DPhil with Jack Baldwin, Oxford 1988. Junior research Fellow, Oxford 1987. University Lecturer in Organic Chemistry, Oxford 1990. Professor of Biological Chemistry, Manchester 1998.