List of Publications 2008-2012 (S L Flitsch)

2012

O'Reilly, Elaine; Aitken, Suzanne J.; Grogan, Gideon; Kelly, Paul P.; Turner, Nicholas J.; Flitsch, Sabine L., Regio- and stereo-selective oxidation of unactivated C-H bonds with Rhodococcus rhodochrous, Beilstein Journal of Organic Chemistry (2012), 8, 496-500, No. 56. Language: English, Database: CAPLUS, DOI:10.3762/bjoc.8.56

Weissenborn, Martin J.; Castangia, Roberto; Wehner, Johannes W.; Sardzik, Robert; Lindhorst, Thisbe K.; Flitsch, Sabine L., Oxo-ester mediated native chemical ligation on microarrays: an efficient and chemoselective coupling methodology, Chemical Communications (Cambridge, United Kingdom) (2012), 48(37), 4444-4446. Language: English, Database: CAPLUS, DOI:10.1039/c2cc30844d

Sardzik, Robert; Green, Anthony P.; Laurent, Nicolas; Both, Peter; Fontana, Carolina; Voglmeir, Josef; Weissenborn, Martin J.; Haddoub, Rose; Grassi, Paola; Haslam, Stuart M.; et al, Chemoenzymatic Synthesis of O-Mannosylpeptides in Solution and on Solid Phase, Journal of the American Chemical Society (2012), 134(10), 4521-4524. Language: English, Database: CAPLUS, DOI:10.1021/ja211861m

McKibbin, Craig; Mares, Alina; Piacenti, Michela; Williams, Helen; Roboti, Peristera; Puumalainen, Marjo; Callan, Anna C.; Lesiak[n.8209]Mieczkowska, Karolina; Linder, Stig; Harant, Hanna; et al, Inhibition of protein translocation at the endoplasmic reticulum promotes activation of the unfolded protein response, Biochemical Journal (2012), 442(3), 639-648. Language: English, Database: CAPLUS, DOI:10.1042/BJ20111220

2011  

Flitsch, Sabine L, Enzymes in Carbohydrate Chemistry, Comprehensive Organic Chemistry (2011) in press

Robin, Aelig; Kohler, Valentin; Jones, Alison; Ali, Afruja; Kelly, Paul P.; O'Reilly, Elaine; Turner, Nicholas J.; Flitsch, Sabine L., Chimeric self-sufficient P450cam-RhFRed biocatalysts with broad substrate scope, Beilstein Journal of Organic Chemistry (2011), 7, 1494-1498, No. 173. Language: English, Database: CAPLUS, DOI:10.3762/bjoc.7.173

Ioannou, Avgousta; Cini, Elena; Timofte, Roxana; Flitsch, Sabine L.; Turner, Nicholas J; Linclau, Bruno, Heavily fluorinated carbohydrates as enzyme substrates: oxidation of tetrafluorinated galactose by galactose oxidase, Chem Commun (2011) 47, 11228–11230

Aletrari, Mina-Olga; McKibbin, Craig; Williams, Helen; Pawar, Vidya; Pietroni, Paola; Lord, J Michael; Flitsch, Sabine L; Whitehead, Roger; Swanton, Eileithyia; High, Stephen; Spooner, Robert A, Eeyarestatin 1 interferes with both retrograde and anterograde intracellular trafficking pathways, PLOS1, (2011) 6(7) e22713

Rannes, Julie; Ioannou, Avgousta; Willies, Simon; Grogan, Gideon; Behrens, Carsten; Flitsch, Sabine; Turner, Nicholas, Glycoprotein labelling using engineered variants of galactose oxidase obtained by directed evolution, J. Am. Chem. Soc. (2011) 133(22), 8436-9. DOI:10.1021/ja2018477 (full text)

Šardzík, Róbert; Sharma, Ritu; Kaloo, Sara; Voglmeir, Josef; Crocker, Paul R.; Flitsch, Sabine L., Chemoenzymatic synthesis of sialooligosaccharides on arrays for studies of cell surface adhesion, Chem. Commun. (2011), 47(19), 5425-7. DOI:10.1039/c1cc10745c (full text)

Voglmeir, Josef; Kaloo, Sara; Laurent, Nicholas; Meloni, Marco M; Bohlmann, Lisa; Wilson, Iain B; Flitsch, Sabine, Biochemical correlation of activity of the alpha-dystroglycan-modifying glycosyltransferase POMGnT1 with mutations in Muscle-Eye-Brain disease. Biochem. J. (2011) 436(2), 447-55. DOI:10.1042/BJ20101059 (full text)

Gotor, Vicente; Flitsch, Sabine L, Increasing the diversity of biocatalytic reactions, Curr Opin Chem Biol (2011), 15(2),185-6

Šardzík, Róbert; Both, Peter; Flitsch, Sabine L, Post-translational modifications – S-linked sugars lost and found, Nature Chem. Biol. (2011) 7(2), 69-70

Alissandratos, Apostolos; Baudendistel, Nina; Hauer, Bernhard; Baldenius, Kai; Flitsch, Sabine L; Halling, Peter J, Biocompatible functionalisation of starch, Chem. Commun., (2011) 47, 683–685

O'Reilly, Elaine; Köhler, Valentin; Flitsch, Sabine L.; Turner, Nicholas J., Cytochromes P450 as useful biocatalysts: addressing the limitations, Chem.Commun. (2011) 47(9), 2490-2501, DOI:10.1039/c0cc03165h (full text)

 2010

Sabbadin, Federico; Hyde, Ralph; Robin, Aelig; Hilgarth, Eva-Maria; Delenne, Marie; Flitsch, Sabine L.; Turner, Nicholas J.; Grogan, Gideon; Bruce, Neil C., LICRED: A Versatile Drop-In Vector for Rapid Generation of Redox-Self-Sufficient Cytochrome P450s, ChemBioChem  (2010), 11(7), 987-994. 

Liem, Kwan-Ping; Noble, Gavin T.; Flitsch Sabine L.; Webb, Simon J., The effect of multivalent binding on the lateral phase separation of adhesive lipids, Faraday Discussions  (2010), 145, 219-233

Tey, Lai-Hock; Loveridge, E.Joel; Swanwick, Richard S., Flitsch Sabine L.; Allemann Rudolf K., Highly site-selective stability increases by glycosylation of dihydrofolate reductase, FEBS JOURNAL (2010) 2 77 (9) , 2171-2179.

Voglmeir, Josef; Šardzík, Robert; Weissenborn Martin J.; Flitsch, Sabine L., Enzymatic glycosylations on arrays, OMICS J. (2010) 14(4), 437-444.

Šardzík, Robert; Noble, Gavin T.; Weissenborn, Martin J.; Martin, Andrew; Webb, Simon J.; Flitsch, Sabine L., Preparation of aminoethyl glycosides for glycoconjugation, Beilstein J. Org. Chem. (2010) 6, 699-703.

Alissandratos, Apostolos; Baudendistel, Nina; Flitsch, Sabine L.; Hauer, Bernhard; Halling, Peter J., Lipase-catalysed acylation of starch and determination of the degree of substitution by methanolysis and GC, BMC Biotechnology (2010) 10, 82.

2009

Robin, Aelig; Roberts, Gareth A.; Kisch, Johannes; Sabbadin, Federico; Grogan, Gideon; Bruce, Neil; Turner, Nicholas J.;Flitsch, Sabine L., Engineering and improvement of the efficiency of a chimeric [P450cam-RhFRed reductase domain] enzyme, Chem. Commun. (2009), (18), 2478-2480. 

Haddoub, Rose; Dauner, Martin; Stefanowicz, Fiona A.; Barattini, Valeria; Laurent, Nicolas; Flitsch, Sabine L., Enzymatic synthesis of peptides on a solid support, Org. Biomol. Chem. (2009) 7, 665–670.

Noble, Gavin T.; Liem, Kwan Ping; Webb, Simon J.; Flitsch, Sabine L., Effect of multivalent binding on the lateral phase separation of mannosylated and biotinylated lipids, Abstracts of Papers, 238th ACS National Meeting, Washington, DC, United States, August 16-20, (2009),ORGN-456.

Haddoub, Rose; Rutzler, Michael; Robin, Aelig; Flitsch, Sabine L., Design, synthesis and assaying of potential aquaporin inhibitors, Handbook of Experimental Pharmacology (2009),190(Aquaporins), 385-402.

Noble, Gavin T.; Flitsch, Sabine L.; Liem, Kwan Ping; Webb, Simon J., Assessing the cluster glycoside effect during the binding of concanavalin A to mannosylated artificial lipid rafts, Org. Biomol. Chem. (2009), 7 (24),5245-5254.

Haddoub, Rose; Laurent, Nicolas; Meloni, Marco M.; Flitsch, Sabine L.; Straightforward synthesis of 2-acetamido-2-deoxy-ß-D-glucopyranosyl esters under microwave conditions, Synlett (2009),(20),3328-3332.

Cross, Benedict C. S.; McKibbin, Craig; Callan, Anna C.; Roboti, Peristera; Piacenti, Michela; Rabu, Catherine; Wilson, Cornelia M.; Whitehead, Roger; Flitsch, Sabine L.; Pool, Martin R.; High, Stephen; Swanton, Eileithyia, Eeyarestatin I inhibits Sec61-mediated protein translocation at the endoplasmic reticulum, Journal of Cell Science (2009), 122(23),4393-4400.

Bahamontes-Rosa Noemi; Bucher Kirsten; Held Jana; Robin Aelig; Hoffmann Wolfgang H.; Flitsch Sabine L., Kremsner Peter G., Kun Juergen F., In vivo anti-malarial effect of the alpha-amino alcohol 1t on Plasmodium berghei, Parasitology Research (2009), 104(6), 1459-1464.

2008

Bahamontes-Rosa, Noemi; Robin, Aelig; Ambrosio, Altair R.; Messias-Reason, Iara T.; Beitz, Eric; Flitsch, Sabine L.; Kun, Juergen F. J., Monoquaternary Ammonium Derivatives Inhibit Growth of Protozoan Parasites, Parasitology International (2008) 57 (2) 132-7.

Karamanska, Rositsa; Clarke, Jonathan; Blixt, Ola; MacRae, James I.; Zhang, Jiquan Q.; Crocker, Paul R.; Laurent, Nicolas; Wright, Adam; Flitsch, Sabine L.; Russell, David A.; Field, Robert A., Surface plasmon resonance imaging for real-time, label-free analysis of protein interactions with carbohydrate microarrays, Glycoconjugate Journal (2008), 25(1), 69-74.

Laurent, Nicolas; Voglmeir, Josef; Wright, Adam; Blackburn, Jonathan; Pham, Nhan T.; Wong, Stephen C. C.; Gaskell, Simon J., Flitsch, Sabine L., Enzymatic glycosylation of peptide arrays on gold surfaces, ChemBioChem (2008) 9, 883-887 .

Zhi, Zheng-liang; Laurent, Nicholas; Powell, Andrew K.; Karamanska, Rositsa, Fais, Margherita; Voglmeir, Josef; Wright, Adam; Blackburn, Jonathan M.; Crocker, Paul R.; Russell, David A.; Flitsch, Sabine L.; Field, Rob A.; Turnbull, Jeremy E., A Versatile Gold Surface Approach for Fabrication and Interrogation of Glycoarrays, ChemBioChem (2008) 9 (10) 1568 – 1575.

Laurent, Nicolas; Haddoub, Rosie and Flitsch, Sabine L., Trends in Biotechnology (2008) 26 328-337.

Laurent, Nicholas; Voglmeir, Josef and Flitsch, Sabine L., Glycoarrays – tools for determining protein-carbohydrate interactions and glycoenzyme specificity, Chem. Commun. (2008) 4371-4384.

Laurent, Nicolas; Haddoub, Rose; Voglmeir, Josef; Wong, Stephen C. C.; Gaskell, Simon J. and Flitsch Sabine L. , SPOT synthesis of peptide arrays on self-assembled monolayers and their evaluation as enzyme substrates, ChemBioChem (2008) 9, 2592-2596.

Deere, Joseph; Halling, Peter; Flitsch, Sabine; De Oliveira, Rui; Tomaszewski, Bartlomiej; Millar, Sarah; Lalaouni, Antonia; Solares, Laura, Kinetics of enzyme attack on substrates covalently attached to solid surfaces: influence of spacer chain length, immobilised substrate surface concentration and surface charge, Langmuir (2008), 24(20),11762-11769. DOI:10.1021/la801932f (full text)